Abel M, Fürste H O, Pringsheim W, Sievers J W, Otto J
Infusionsther Klin Ernahr. 1984 Oct;11(5):267-9.
Erythrocyte concentrates are preferred increasingly to whole-blood transfusions in treatment of neonatal anemias. By means of their application even very important restorations of hematocrit are possible without the risk of fluid overload. A possible side-effect of these erythrocyte suspensions is a transfusion mediated acidosis, which depends on the used buffer solution, temperature and storage conditions before and during use. The case report of a preterm infant with Rh-Erythroblastosis and postpartal shock demonstrates the problem of an additional acidosis caused by the ACD-adenin stabilised erythrocyte concentrate. The impression of a transfusion mediated acidaemia is confirmed by 30 comparative pH-measurements in ACD-adenin and heparin stored erythrocytes. We conclude that erythrocyte transfusions in very ill neonates with severe disturbances of metabolism and reduced organ functions should be done with heparin erythrocyte preparations.
在治疗新生儿贫血时，红细胞浓缩物越来越多地被优先用于全血输血。通过使用红细胞浓缩物，即使血细胞比容得到非常重要的恢复，也不会有液体过载的风险。这些红细胞悬液的一个可能的副作用是输血介导的酸中毒，这取决于所使用的缓冲溶液、温度以及使用前和使用期间的储存条件。一名患有Rh - 红细胞增多症和产后休克的早产儿的病例报告显示了由ACD - 腺嘌呤稳定的红细胞浓缩物引起的额外酸中毒问题。通过对ACD - 腺嘌呤和肝素储存的红细胞进行30次对比pH测量，证实了输血介导的酸血症的印象。我们得出结论，对于患有严重代谢紊乱和器官功能减退的重病新生儿，应使用肝素红细胞制剂进行红细胞输血。
