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[宫内输血后新生儿的Rh血型不合性酸中毒]

[Rh-incompatibility acidosis in newborn infants following intrauterine transfusion].

作者信息

Siebers J W

出版信息

Geburtshilfe Frauenheilkd. 1985 Aug;45(8):552-3. doi: 10.1055/s-2008-1036367.

Abstract

Severe foetal Rh erythroblastosis is treated by intrauterine transfusion, in most cases with ACD adenine erythrocyte concentrates. In two cases where delivery took place shortly after the last intrauterine transfusion, metabolic acidosis developed post partum, which could possibly be attributed to the erythrocyte concentrates in the transfusion. Multiple pH level measurements in the ACD adenine erythrocyte concentrates revealed pH levels between 6.4 and 6.8. Erythrocyte concentrates prepared with heparin showed pH levels between 7.18 and 7.25 and should therefore be used for intrauterine transfusion in place of ACD adenine erythrocyte concentrates.

摘要

严重的胎儿Rh溶血病通过宫内输血治疗,多数情况下使用ACD腺嘌呤红细胞浓缩液。在两例最后一次宫内输血后不久即分娩的病例中,产后出现了代谢性酸中毒,这可能归因于输血中的红细胞浓缩液。对ACD腺嘌呤红细胞浓缩液进行的多次pH值测量显示,pH值在6.4至6.8之间。用肝素制备的红细胞浓缩液pH值在7.18至7.25之间,因此应用于宫内输血以取代ACD腺嘌呤红细胞浓缩液。

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