Ellman B A, Parkhill B J, Marcus P B, Curry T S, Peters P C
Invest Radiol. 1984 Sep-Oct;19(5):416-23. doi: 10.1097/00004424-198409000-00014.
The mechanism of renal ablation by intra-arterial ethanol was studied in 16 mongrel dogs. Ethanol injection rates were varied, and light and electron microscopic studies were performed to detect early parenchymal changes in the kidneys. Pure ischemic injury was also studied as a control. Findings showed extensive parenchymal injury plays a significant role in renal ablation with permanent thrombosis as a delayed event. Acute arterial occlusion occurred with slow ethanol injection rates due to embolization by damaged blood components.
在16只杂种犬中研究了经动脉内注射乙醇进行肾消融的机制。改变乙醇注射速率，并进行光镜和电镜研究以检测肾脏实质的早期变化。还研究了单纯缺血性损伤作为对照。结果显示，广泛的实质损伤在肾消融中起重要作用，永久性血栓形成是延迟发生的事件。由于受损血液成分的栓塞，缓慢注射乙醇会导致急性动脉闭塞。
