Héry M, Namer M, Verschoore J, Monticelli J, Boublil J L, Lalanne C M
Int J Radiat Oncol Biol Phys. 1984 Dec;10(12):2185-90. doi: 10.1016/0360-3016(84)90222-0.
Between 1975 and 1980, 108 breast cancers (T1 and small T2) were treated at the Centre Antoine-Lacassagne (Nice, France) by a combination of conservative surgery and irradiation. Ninety-two of these patients underwent axillary node dissection; 17% of them presented with nodal involvement. All irradiation was given by telecobalt: 45 Gy to the entire breast, 60 Gy to the site of the tumor. All cosmetic results were acceptable. Intramammary recurrences were rare (6%) and independent of the tumor site or size or of any nodal involvement. Solitary metastases (not associated with a local recurrence) were extremely rare (4%) and were observed in patients who had had no nodal involvement. The actuarial survival rate at 5 years is 90%.
1975年至1980年间,法国尼斯市安托万 - 拉卡萨涅中心对108例乳腺癌(T1期和小T2期)患者采用了保乳手术和放疗相结合的治疗方法。其中92例患者接受了腋窝淋巴结清扫术,17%的患者出现淋巴结受累。所有放疗均采用远距离钴治疗:全乳照射45 Gy,肿瘤部位照射60 Gy。所有患者的美容效果均可接受。乳腺内复发很少见(6%),且与肿瘤部位、大小或淋巴结受累情况无关。孤立性转移(与局部复发无关)极为罕见(4%),仅在无淋巴结受累的患者中观察到。5年精算生存率为90%。