Pierquin B, Otmezguine Y, Lobo P A
Acta Radiol Oncol. 1983;22(2):101-7. doi: 10.3109/02841868309134347.
The results of conservative management of breast carcinoma are presented. The disease free survival for patients with T1 lesions was 84 per cent at 5 years, 76 per cent at 7 years and 65 per cent at 10 years, for T2 75, 71 and 64 per cent, and for T3 65, 51 and 45 per cent. The proportion of breast conserved amongst the patients free of disease at 10 years was 94 per cent for T1, 93 per cent for T2 and 80 per cent for patients with T3 lesions. The cosmetic results were very good for T1 lesions, good for T2 and quite good for T3 lesions. Up to 1981 a simple tumorectomy was carried out in most of the T1 lesions and some of the T2 lesions, followed by radical irradiation. Most of the T2 and T3 lesions were exclusively treated with radical irradiation. In an attempt to improve the cosmetic results, since 1981, the indications for tumorectomy were extended to include some of the T2 lesions, and when possible also some of the T3 lesions, where a tumorectomy is performed before or after irradiation, together with a limited axillary dissection.
本文展示了乳腺癌保守治疗的结果。T1期病变患者的无病生存率在5年时为84%，7年时为76%，10年时为65%；T2期分别为75%、71%和64%；T3期分别为65%、51%和45%。在10年无病的患者中，T1期保乳患者比例为94%，T2期为93%，T3期病变患者为80%。T1期病变的美容效果非常好，T2期良好，T3期相当不错。截至1981年，大多数T1期病变以及部分T2期病变采用单纯肿瘤切除术，随后进行根治性放疗。大多数T2期和T3期病变仅接受根治性放疗。为了改善美容效果，自1981年起，肿瘤切除术的适应证扩大至包括部分T2期病变，并且在可能的情况下也包括部分T3期病变，即在放疗前后进行肿瘤切除术，并同时进行有限的腋窝淋巴结清扫。
