Fialkov M J, Hasley S
J Dev Behav Pediatr. 1984 Dec;5(6):325-30.
Over an 11-month period on a Children's Psychiatric Unit 5% of 60 first admissions for hospitalization were apparently associated with adverse effects of psychotropic medication. Forty (66%) of the first admissions had used, prior to hospitalization, a wide variety of drugs including stimulants, major and minor tranquilizers, anticonvulsants, antidepressants and over-the-counter drugs containing antihistamines and analgesics. It is suggested that inappropriate and injudicious use of psychotropic medications may be associated with unanticipated adverse behavioral effects, which can result in deterioration of a child's functioning to the point of necessitating psychiatric hospitalization. Early identification of these unwanted psychotropic effects has diagnostic, prognostic, economic, and legal implications.
在一家儿童精神科病房为期11个月的时间里,60名首次住院患者中有5%的情况显然与精神药物的不良反应有关。40名(66%)首次住院患者在住院前使用过多种药物,包括兴奋剂、大剂量和小剂量镇静剂、抗惊厥药、抗抑郁药以及含有抗组胺药和镇痛药的非处方药。有人认为,精神药物的不当和不合理使用可能与意外的不良行为影响有关,这可能导致儿童功能恶化,直至需要精神科住院治疗。尽早识别这些不良的精神药物影响具有诊断、预后、经济和法律方面的意义。