Gitlin M J, Weiss J
J Clin Psychopharmacol. 1984 Dec;4(6):341-3.
The authors report the successful maintenance treatment of a bipolar woman with verapamil. Whereas the patient had previously demonstrated multiple antidepressant-induced manias despite prophylactic lithium treatment, she was able to maintain on verapamil plus trazodone without manic or depressive episodes over a 1-year period. It is suggested that verapamil may have a place in the maintenance treatment of bipolar patients.
作者报告了使用维拉帕米成功维持治疗一名双相情感障碍女性患者的案例。该患者此前尽管接受了预防性锂盐治疗，但仍多次出现抗抑郁药诱发的躁狂发作，而在维拉帕米加曲唑酮治疗下，她在1年时间里得以维持稳定，未出现躁狂或抑郁发作。提示维拉帕米在双相情感障碍患者的维持治疗中可能占有一席之地。
