Pournaras C, Tsacopoulos M
Klin Monbl Augenheilkd. 1978 Apr;172(4):445-8.
The microioptophoretic injection of PGE1 close to the retinal arterioles procedures a segmental vasodilatation of 40%. The inhibition of prostaglandin synthesis with indomethacin or aspirin blocks the vasodilatatory effect of hypercapnia and, to a lesser extent, of hypoxia. These results suggest that prostaglandins play a role in the regulation of retinal vasomotor activity.
在视网膜小动脉附近微量注射前列腺素E1可使局部血管扩张40%。用消炎痛或阿司匹林抑制前列腺素合成可阻断高碳酸血症的血管扩张作用,并在较小程度上阻断低氧血症的血管扩张作用。这些结果表明,前列腺素在视网膜血管舒缩活动的调节中起作用。