无运动性纤毛的纯合小鼠中的内脏反位。
Situs inversus in homozygous mice without immotile cilia.
作者信息
Handel M A, Kennedy J R
出版信息
J Hered. 1984 Nov-Dec;75(6):498. doi: 10.1093/oxfordjournals.jhered.a109995.
Abstract
Mice homozygous for the mutation situs inversus, iv, are characterized by situs inversus in 50 percent of the individuals. We have investigated the ultrastructure and motility of tracheal cilia and sperm tails in homozygous individuals with and without situs inversus. We found no abnormalities of ciliary structure. Therefore, ciliary immotility is not an essential correlate of situs inversus.
摘要
纯合子突变“内脏逆位，iv”的小鼠中，50%的个体具有内脏逆位特征。我们研究了有或没有内脏逆位的纯合子个体中气管纤毛和精子尾部的超微结构及运动性。我们未发现纤毛结构异常。因此，纤毛运动障碍并非内脏逆位的必要相关因素。
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