Turkheimer E, Cullum C M, Hubler D W, Paver S W, Yeo R A, Bigler E D
J Neurol Neurosurg Psychiatry. 1984 Dec;47(12):1314-8. doi: 10.1136/jnnp.47.12.1314.
Most of the methods of quantifying cortical atrophy that have been proposed involve the estimation of the volume of enlarged sulci in the cerebral cortex. The authors propose that the surface area of the sulci is a more valid measure of cortical atrophy, and describe a system for measuring the surface area of the cortex, and present data in support of the method's reliability and validity.
大多数已提出的量化皮质萎缩的方法都涉及对大脑皮质中增宽脑沟体积的估计。作者提出脑沟的表面积是衡量皮质萎缩更有效的指标,并描述了一种测量皮质表面积的系统,还给出了支持该方法可靠性和有效性的数据。