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头孢西丁治疗呼吸道感染的临床研究

[Clinical studies on cefoxitin in the treatment of respiratory tract infections].

作者信息

Kuwabara M, Kodomari Y, Jyo T, Kuraoka T, Mitsuyama T, Kodomari N, Iwamoto K, Miyazawa T, Watanabe T, Morikawa E

出版信息

Jpn J Antibiot. 1984 Sep;37(9):1685-93.

PMID:6512985
Abstract

The clinical effects of cefoxitin (CFX) were studied in 31 cases of respiratory tract infections. The results were as follows: As for the clinical effects, CFX was excellent in 5 cases, good in 13, fair in 8 and poor in 5 out of 31 patients; the efficacy rate was 58.1%. The efficacy rate was 57.1% in bronchopneumonia, 61.1% in pneumonia and 50.0% in acute exacerbation of chronic respiratory tract infections. The efficacy rate was 70.6% in the group of 4 g/day or less and 42.9% in the group of 6 g/day or more. The efficacy rate was 50.0% in 6 cases that had not been responded to other antibiotics previously. As for side effects, skin eruption was observed in only 1 patient. No abnormality was observed in laboratory tests due to CFX. In conclusion, CFX is a useful drug in the treatment of respiratory tract infections.

摘要

对31例呼吸道感染患者研究了头孢西丁(CFX)的临床疗效。结果如下:就临床疗效而言,31例患者中,CFX疗效优者5例,良者13例,中者8例,差者5例;有效率为58.1%。支气管肺炎有效率为57.1%,肺炎为61.1%,慢性呼吸道感染急性加重为50.0%。每日4g及以下组有效率为70.6%,每日6g及以上组为42.9%。既往对其他抗生素无反应的6例患者中有效率为50.0%。至于副作用,仅1例患者出现皮疹。未观察到因CFX导致的实验室检查异常。总之,CFX是治疗呼吸道感染的一种有用药物。

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