Imataka K, Seki A, Takahashi N, Fujii J
Jpn Heart J. 1984 Sep;25(5):725-31. doi: 10.1536/ihj.25.725.
Vascular murmurs were routinely sought over the carotid arteries in 1,777 outpatients of 40 years of age or older who attended the cardiovascular clinic of our institute, and carotid bruits were heard in 82 patients (4.6%). The prevalence of carotid bruits increased with age from 5/467 (1.1%) in patients aged 40 to 49 years to 26/150 (17.3%) in those aged 70 to 79 years. Calcification of the carotid arteries was examined by posteroanterior films of the cervical spine in 447 patients 60 years of age or older and carotid calcification was found in 20 (42.6%) of 47 patients with carotid bruits and in 50 (12.5%) of 400 patients without them. The incidence of carotid calcification in the former group was 3.4 times that in the latter (p less than 0.01), although the incidences of hypertension and glucose intolerance were not related to the presence or absence of carotid bruits. A history of cerebral bleeding or infarction was found in 19 (23.2%) of 82 patients with carotid bruits, as compared with 64 (3.8%) of 1,695 patients without them (p less than 0.01). However, the location of the cerebrovascular lesions did not necessarily correlate with the laterality of the carotid bruits. These results indicate that patients with carotid bruits show an increased risk of stroke and that these bruits are a general and non-focal sign of severe atherosclerotic cerebrovascular disease.
在我院心血管门诊就诊的1777名40岁及以上的门诊患者中，常规检查了颈动脉有无血管杂音，其中82例（4.6%）可闻及颈动脉杂音。颈动脉杂音的患病率随年龄增长而增加，从40至49岁患者中的5/467（1.1%）增至70至79岁患者中的26/150（17.3%）。对447名60岁及以上患者的颈椎正位片进行检查以评估颈动脉钙化情况，结果发现，在47例有颈动脉杂音的患者中有20例（42.6%）存在颈动脉钙化，而在400例无颈动脉杂音的患者中有50例（12.5%）存在颈动脉钙化。尽管高血压和糖耐量异常的发生率与有无颈动脉杂音无关，但前一组的颈动脉钙化发生率是后一组的3.4倍（p<0.01）。82例有颈动脉杂音的患者中有19例（23.2%）有脑出血或脑梗死病史，而在1695例无颈动脉杂音的患者中有64例（3.8%）有上述病史（p<0.01）。然而，脑血管病变的部位不一定与颈动脉杂音的侧别相关。这些结果表明，有颈动脉杂音的患者中风风险增加，且这些杂音是严重动脉粥样硬化性脑血管疾病的一个常见而非局灶性体征。
