Cooperman M, Martin E W, Evans W E
Arch Surg. 1978 Nov;113(11):1339-40. doi: 10.1001/archsurg.1978.01370230129016.
To assess the significance of the asymptomatic carotid bruit, the subsequent occurrence of symptomatic cerebrovascular insufficiency and stroke in 256 patients who had undergone operation for atherosclerosis arterial occlusive disease of the lower extremities was documented during a period of two to seven years postoperatively. At the time of operation, none had had a stroke or exhibited symptoms of cerebrovascular insufficiency, but 60 of the 256 patients had audible carotid bruits. A statistically significant difference was demonstrated: 21 (35%( of the 60 patients with carotid bruits exhibited manifestations of cerebrovascular insufficiency, in contrast to 30 (16%) of the 196 patients without bruits. It seems that detection of an asymptomatic carotid bruit is not an innocent finding, but rather predicts a higher incidence of cerebrovascular complications than that expected on the basis of generalized atherosclerosis alone.
为评估无症状性颈动脉杂音的意义，对256例接受下肢动脉粥样硬化闭塞症手术的患者在术后2至7年期间记录了随后出现的有症状性脑血管功能不全和中风情况。手术时，无一例发生中风或表现出脑血管功能不全症状，但256例患者中有60例可闻及颈动脉杂音。结果显示出具有统计学意义的差异：60例有颈动脉杂音的患者中有21例（35%）出现脑血管功能不全表现，相比之下，196例无杂音患者中有30例（16%）出现该表现。似乎检测到无症状性颈动脉杂音并非无足轻重的发现，而是预示着脑血管并发症的发生率高于仅基于全身性动脉粥样硬化所预期的发生率。
