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[用多元回归法评估动物对低氧性缺氧的适应性]

[Evaluation of adaptation of animals to hypoxic hypoxia by the multiple regression method].

作者信息

Kustov V V, Litau V G, Kukushkin Iu A, Razinkin S M

出版信息

Kosm Biol Aviakosm Med. 1984 Nov-Dec;18(6):67-9.

PMID:6513489
Abstract

White mice were exposed to hypoxic hypoxia during 30 days. In the study a correlation between the altitude ceiling and various physiological parameters (body weight, body temperature variations in response to a cold stress (5 degrees C), hemoglobin content, coefficients of adaptive oxygen consumption determined as the ratio of oxygen consumption at 6000 m to that at sea level (K1) and the ratio of oxygen consumption in hypoxic environment to that in a normoxic atmosphere (K2) was established. The data obtained allow the conclusion that the multiple regression method can be used for measuring objectively the tension of regulatory systems and for discriminating stages of animal adaptation to hypoxic hypoxia.

摘要

将小白鼠暴露于低氧环境30天。在该研究中,确定了海拔上限与各种生理参数(体重、对冷应激(5摄氏度)的体温变化、血红蛋白含量、适应耗氧量系数,适应耗氧量系数定义为6000米处的耗氧量与海平面处的耗氧量之比(K1)以及低氧环境中的耗氧量与常氧环境中的耗氧量之比(K2))之间的相关性。所得数据表明,多元回归方法可用于客观测量调节系统的紧张程度以及区分动物对低氧环境适应的阶段。

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