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[神经外科领域的一种新材料]

[A new material in neurosurgery].

作者信息

Krähling K H, König H J

出版信息

Neurochirurgia (Stuttg). 1984 Nov;27(6):166-9. doi: 10.1055/s-2008-1054213.

Abstract

A new alcoholic prolamine solution is now available (ETHIBLOC, supplied by Ethicon, Norderstedt) which can be used in neurosurgery for a variety of purposes. This material hardens quickly in an aqueous medium. Animal experiments have not shown any damaging action on the brain, meninges, or bone. The excellent tolerance of the material was seen in a total of 22 patients operated on with the help of Ethibloc. It is particularly well suited for closing frontal CSF fistulas, incised frontal sinuses, and for rearranging or shunting in case of cerebral vascular deformities. It can also be used as a carrier of antibiotics in osteomyelitis, for covering up minor defects of the dura mater, for dura sealing, and for closing the bone after trephination. The preparation is transformed completely to connective tissue within a period of 40 to 90 days. New techniques of surgery are described which have become possible by the use of Ethibloc.

摘要

现在有一种新的酒精性醇溶谷蛋白溶液可供使用(ETHIBLOC,由位于诺德施泰特的Ethicon公司提供),可用于神经外科的多种用途。这种材料在水性介质中会迅速硬化。动物实验未显示其对大脑、脑膜或骨骼有任何损害作用。在总共22例借助ETHIBLOC进行手术的患者中,观察到该材料具有极佳的耐受性。它特别适用于封闭额部脑脊液瘘、切开的额窦,以及在脑血管畸形的情况下进行重新排列或分流。它还可在骨髓炎中用作抗生素载体,用于覆盖硬脑膜的小缺损、进行硬脑膜密封以及在钻孔后封闭骨骼。该制剂在40至90天内会完全转化为结缔组织。文中描述了借助ETHIBLOC得以实现的新手术技术。

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