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影响孕期酒精暴露结局的因素:I. 产次。

Factors affecting the outcome of maternal alcohol exposure: I. Parity.

作者信息

Abel E L, Dintcheff B A

出版信息

Neurobehav Toxicol Teratol. 1984 Sep-Oct;6(5):373-7.

PMID:6514101
Abstract

Despite relatively comparable amounts of alcohol ingestion, not all women who drink excessively give birth to children with fetal alcohol effects. One reason for this differential effect may be maternal parity. To explore this question, pregnant rats of the same age but different parities (first and fourth pregnancy) were intubated during pregnancy with alcohol. Whereas both parity and alcohol exposure independently affected birth weight and perinatal mortality, there was no interaction between the two suggesting that parity per se is not a factor contributing to the differential effects of maternal alcohol consumption on offspring.

摘要

尽管摄入的酒精量相对相当,但并非所有酗酒的女性都会生下患有胎儿酒精影响的孩子。这种差异效应的一个原因可能是母亲的生育次数。为了探究这个问题,将相同年龄但不同生育次数(首次怀孕和第四次怀孕)的怀孕大鼠在孕期通过插管给予酒精。虽然生育次数和酒精暴露都独立影响出生体重和围产期死亡率,但两者之间没有相互作用,这表明生育次数本身并不是导致母亲饮酒对后代产生差异效应的一个因素。

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Factors affecting the outcome of maternal alcohol exposure: I. Parity.影响孕期酒精暴露结局的因素:I. 产次。
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Factors affecting the outcome of maternal alcohol exposure: II. Maternal age.影响孕期酒精暴露结局的因素:II. 母亲年龄。
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The causal web of foetal alcohol spectrum disorders: a review and causal diagram.胎儿酒精谱系障碍的因果网络:综述和因果图。
Eur Child Adolesc Psychiatry. 2020 May;29(5):575-594. doi: 10.1007/s00787-018-1264-3. Epub 2019 Jan 16.
2
Eye malformations in children with heavy alcohol exposure in utero.孕期大量接触酒精的儿童的眼部畸形
J Pediatr. 2008 Sep;153(3):391-5. doi: 10.1016/j.jpeds.2008.04.024. Epub 2008 Jun 20.