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孕酮对仓鼠特定交配刺激下脊柱前凸反应的影响。

Effects of progesterone on lordotic responses to specific mating stimuli in hamsters.

作者信息

Buntin J D, Lisk R D

出版信息

Physiol Behav. 1984 Sep;33(3):491-4. doi: 10.1016/0031-9384(84)90174-4.

DOI:10.1016/0031-9384(84)90174-4
PMID:6514837
Abstract

Mating-induced inhibition of sexual receptivity was examined in ovariectomized, estrogen (E) treated and estrogen plus progesterone (E + P) treated hamsters given 10 min of exposure to male mounting stimulation alone or to mounts, intromissions, and ejaculations at eight hourly intervals. In E + P treated females, no differential effects of exposure to full mating stimulation vs. mounting stimulation alone were observed. In contrast, females given E treatment alone showed a marked differential response. Fully mated, E-treated females showed more lordosis than E-treated females exposed to mounts alone during the initial test. However, total lordosis duration declined precipitiously in the fully mated group by 2 hr and remained significantly below that in other groups during subsequent tests. Levels of receptivity in E-treated females mounted-only remained relatively constant until 8 hr. These results suggest that P reduces the inhibitory effects of vaginocervical cues received during mating without affecting the response to mounting stimulation alone. In addition, vaginocervical stimulation may initially facilitate lordosis in E-treated females.

摘要

在接受卵巢切除术、单独给予雌激素(E)处理以及雌激素加孕激素(E + P)处理的仓鼠中,研究了交配诱导的性接受抑制情况。这些仓鼠以八小时为间隔,分别接受10分钟的单独雄性爬跨刺激,或接受爬跨、插入和射精的完整交配刺激。在接受E + P处理的雌性仓鼠中,未观察到暴露于完整交配刺激与单独爬跨刺激之间的差异效应。相比之下,仅接受E处理的雌性仓鼠表现出明显的差异反应。在初次测试中,完全交配的E处理雌性仓鼠比仅接受爬跨刺激的E处理雌性仓鼠表现出更多的脊柱前凸。然而,完全交配组的总脊柱前凸持续时间在2小时时急剧下降,并且在后续测试中显著低于其他组。仅接受爬跨刺激的E处理雌性仓鼠的接受水平在8小时前保持相对稳定。这些结果表明,孕激素可降低交配过程中阴道宫颈线索的抑制作用,而不影响对单独爬跨刺激的反应。此外,阴道宫颈刺激最初可能会促进E处理雌性仓鼠的脊柱前凸。

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