Seibert J J, Seibert R W, Weisenburger D S, Allsbrook W
Laryngoscope. 1978 Jun;88(6):1006-12. doi: 10.1288/00005537-197806000-00012.
Hemangiopericytoma is a vascular tumor arising from contractile cells, the pericyte of Zimmermann. The neoplasms most frequently involve deep musculature; however, 16% occur in the head and neck region. The case presented here represents the rare occurrence of multiple congenital hemangiopericytoma of the head and neck. In older patients, these rather poorly differentiated tumors recur locally after excision in 50%-80% of cases depending on the organ site involved. Distant metastasis to lung or bone may follow. Congenital hemangiopericytomas appear to follow a more benign clinical course, possibly due to a more superficial location and a tendency to transform into hemangioendotheliomas. Recommended treatment is wide local excision and long-term follow-up.
血管外皮细胞瘤是一种起源于收缩细胞(齐默尔曼周细胞)的血管肿瘤。该肿瘤最常累及深部肌肉组织;然而,16%发生在头颈部区域。本文报道的病例是罕见的头颈部多发性先天性血管外皮细胞瘤。在老年患者中,这些分化较差的肿瘤根据受累器官部位不同,50%-80%在切除后会局部复发。随后可能发生肺或骨的远处转移。先天性血管外皮细胞瘤似乎具有更良性的临床病程,可能是由于其位置较表浅且有转化为血管内皮瘤的倾向。推荐的治疗方法是广泛局部切除并进行长期随访。