Hicks G W, Wright J W, Wright J W
Laryngoscope. 1978 Jun;88(6):1024-33. doi: 10.1288/00005537-197806000-00015.
With the exception of stapes prostheses, previous use of implantable alloplastic materials in reconstructing the sound conducting mechanism in middle ear surgery has been uniformly unsuccessful. A new material composed of ultra-high molecular weight polyethylene has been developed as a replacement for middle ear ossicles. This implant, called the Plastipore total ossicular replacement prosthesis (TORP), and the Plastipore drum to the stapes prosthesis were inserted in 87 patients, all of whom had a long history of extensive middle ear disease and/or surgery. One TORP patient was lost to follow-up. The overall average hearing gain was 14.8 db. The overall follow-up was 12.4 months with a range of from 3 to 25 months. Eleven of the 15 patients receiving the drum-to-stapes prosthesis had hearing gain; 55 of 71 patients receiving the TORP had hearing gain. Eight prostheses were extruded. Nine patients had no improvement in hearing. Eight patients had subsequent decrease in hearing after initial gains. All ears are now dry and aerated. Early evaluation appears to demonstrate that the Plastipore prosthesis shows promise for use in difficult reconstructive middle ear problems.
除镫骨假体之外，以往在中耳手术中使用可植入的异质成形材料重建传音机制均未成功。一种由超高分子量聚乙烯制成的新型材料已被研发出来用于替代中耳听小骨。这种植入物名为Plastipore全听骨置换假体（TORP），还有Plastipore鼓膜到镫骨假体，被植入了87例患者体内，所有这些患者都有长期广泛的中耳疾病和/或手术史。1例接受TORP植入的患者失访。总体平均听力增益为14.8分贝。总体随访时间为12.4个月，范围从3个月至25个月。接受鼓膜到镫骨假体植入的15例患者中有11例听力得到改善；接受TORP植入的71例患者中有55例听力得到改善。8个假体发生了脱出。9例患者听力没有改善。8例患者在最初听力提高后听力随后下降。目前所有术耳均已干耳且通气良好。早期评估似乎表明，Plastipore假体在解决复杂的中耳重建问题方面具有应用前景。
