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[极低热量生酮饮食对肥胖受试者血浆脂质和脂蛋白的影响]

[Effect of the PSMF diet on plasma lipids and lipoproteins in obese subjects].

作者信息

Petrillo A, Chevaux F, Rohrer J, Darioli R

出版信息

Schweiz Med Wochenschr. 1984 Dec 8;114(49):1837-41.

PMID:6515380
Abstract

The influence of weight reduction on plasma lipids, lipoproteins and apoproteins was studied in 14 patients (8 females and 6 males) with varying degrees of obesity. After 4 weeks on hypocaloric diet (PSMF), an 8% weight loss was associated with a significant decrease in total cholesterol (18%), triglycerides (47%) and phospholipids (20%). No significant change was observed in HDL-cholesterol. The HDL-cholesterol/total cholesterol ratio was increased. The greatest decrease was observed in VLDL fractions. The decreases in apoprotein A and B were 19% and 15% respectively. These findings indicate that favourable changes in plasma lipoproteins are achieved after weight loss on hypocaloric diet.

摘要

对14名不同程度肥胖的患者(8名女性和6名男性)进行了体重减轻对血浆脂质、脂蛋白和载脂蛋白影响的研究。在低热量饮食(蛋白质节省型改良禁食法)4周后,体重减轻8%与总胆固醇(18%)、甘油三酯(47%)和磷脂(20%)的显著降低相关。高密度脂蛋白胆固醇未观察到显著变化。高密度脂蛋白胆固醇与总胆固醇的比值升高。极低密度脂蛋白部分下降最为明显。载脂蛋白A和B分别下降了19%和15%。这些发现表明,低热量饮食减肥后血浆脂蛋白会出现有利变化。

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