MacKenzie G, Hunter A R, Ross J G
Vet Res Commun. 1984 Nov;8(4):283-92. doi: 10.1007/BF02214723.
A number of immuno-competent Blackface lambs were infected with 10,000 Haemonchus contortus third stage larvae and were later challenged with a second dose of 10,000 H. contortus third stage larvae. One group of lambs was treated with dialysed transfer factor prior to the second challenge dose. Histological changes in the abomasal wall, reductions in abomasal worm burdens at slaughter and faecal egg counts monitored throughout the experiment suggested the presence in some animals of an innate resistance, a "self curing" effect, an enhancement of this "self curing" effect in the transfer factor treated group and a response in one transfer factor treated animal comparable to "classical self cure".
将若干具有免疫能力的黑脸羔羊感染10,000条捻转血矛线虫第三期幼虫，随后用第二剂10,000条捻转血矛线虫第三期幼虫进行攻毒。一组羔羊在第二次攻毒剂量之前接受了透析转移因子治疗。整个实验过程中监测到的皱胃壁组织学变化、屠宰时皱胃内蠕虫负荷的减少以及粪便虫卵计数表明，一些动物存在先天抵抗力、“自愈”效应，在转移因子治疗组中这种“自愈”效应得到增强，并且在一只接受转移因子治疗的动物中出现了与“经典自愈”相当的反应。
