Heberling H J, Gauer J, Dieterich F, Kuhlmann E, Wünsch C, Lohmann D
Z Gesamte Inn Med. 1984 Oct 15;39(20):508-10.
In the period from 1976 to September 1982 39 patients with the clinical diagnosis of primary hyperparathyroidism were operated on. Among then were 24 women and 14 men. The most frequent manifestation form is the renal one (n = 26). The proportion of patients with hypercalcaemic crisis was very large (n = 4). Topographically and anatomically the adenomas were most frequently found in the region of the right lower pole of the thyroid gland. 23 patients had a singular adenoma, 11 patients showed multiple adenomas and only 2 had a diffuse hyperplasia. In patients with persisting hyperparathyroidism before a repeated intervention an attempt of localization should be performed by a selective phlebography with taking of blood samples for the determination of PTH. The success of the operation is to be read off most clearly at the behaviour of the post-operative values of serum calcium. In 29 patients a normocalcaemia was achieved. 6 patients showed at first a hypocalcaemia, which however, was only temporary in 4 patients. 3 patients had a persisting hyperparathyroidism. In accordance with the literary data the formation of renal calculi clearly decreased after a successful operation.
在1976年至1982年9月期间，对39例临床诊断为原发性甲状旁腺功能亢进症的患者进行了手术。其中女性24例，男性14例。最常见的表现形式是肾脏方面的（n = 26）。高钙血症危象患者的比例非常高（n = 4）。从局部解剖学角度来看，腺瘤最常出现在甲状腺右下极区域。23例患者有单个腺瘤，11例患者有多发性腺瘤，只有2例有弥漫性增生。对于反复干预前仍存在甲状旁腺功能亢进的患者，应通过选择性静脉造影并采集血样测定甲状旁腺激素来进行定位尝试。手术的成功与否从术后血清钙值的变化情况最能清楚看出。29例患者实现了血钙正常。6例患者起初出现低钙血症，但其中4例只是暂时的。3例患者持续存在甲状旁腺功能亢进。与文献数据一致，成功手术后肾结石的形成明显减少。
