Wendt F, Geipel D
I. Clinic of Surgery, Klinikum Berlin-Buch, GDR.
Exp Clin Endocrinol. 1989 Sep;94(1-2):163-70. doi: 10.1055/s-0029-1210893.
60 patients suffering from primary hyperparathyroidism were operated during the period from 1980 till september 1988. The operation was successful in 55 cases. Most patients had single adenomas of the parathyroid glands. There was only one case with a four-gland-hyperplasia and one case with a parathyroid carcinoma. Rare observations were: one woman with a truly recurrent primary hyperparathyroidism, two patients with a papillary carcinoma of the thyroid gland in addition to the hyperparathyroidism and one patient with a large cystic parathyroid adenoma. Most of the patients had severe clinical symptoms of the primary hyperparathyroidism, mainly renal stones, in some cases bone changes. Only three patients were asymptomatic.
1980年至1988年9月期间,对60例原发性甲状旁腺功能亢进患者进行了手术。55例手术成功。大多数患者患有甲状旁腺单发性腺瘤。只有1例四腺增生和1例甲状旁腺癌。罕见的情况有:1例真正复发性原发性甲状旁腺功能亢进的女性患者,2例除甲状旁腺功能亢进外还患有甲状腺乳头状癌的患者,以及1例巨大囊性甲状旁腺腺瘤患者。大多数患者有原发性甲状旁腺功能亢进的严重临床症状,主要是肾结石,有些病例有骨骼改变。只有3例无症状。