Paravicini D, Wasylewski A H, Rassat J, Thys J
Acta Anaesthesiol Belg. 1984;35 Suppl:43-9.
In an animal experimental model the survival of untreated red blood cells (RBC) tagged with 51Cr was compared with cells processed by an autotransfusion device separating and washing the RBC tagged with 111In. Intraoperative autotransfusion (IAT) was done by the Haemonetics Cell Saver. Additionally the morphology of human RBC was investigated in different stages of IAT by the aid of scanner electron micrographs. The survival of RBC after processing was slightly decreased in comparison to untreated cells. The morphology of autologous RBC is little affected compared with older homologous RBC in erythrocytic concentrates. Cell detritus due to haemolysis is reliably eliminated by microfiltration. Especially regarding survival and morphologic alterations of RBC IAT with a system separating and washing the cells seems to be superior to the transfusion of homologous blood.
在动物实验模型中，将未处理的用51Cr标记的红细胞（RBC）的存活率与通过自动输血装置处理的用111In标记的红细胞进行分离和洗涤后的细胞存活率进行了比较。术中自动输血（IAT）由Haemonetics细胞回收器完成。此外，借助扫描电子显微镜研究了IAT不同阶段人红细胞的形态。与未处理的细胞相比，处理后红细胞的存活率略有下降。与红细胞浓缩物中较陈旧的同源红细胞相比，自体红细胞的形态受影响较小。通过微滤可可靠地消除溶血导致的细胞碎屑。特别是在红细胞的存活率和形态改变方面，使用分离和洗涤细胞的系统进行IAT似乎优于输注同源血液。
