Ansell J, Parrilla N, King M, Fournier L, Szymanski I, Doherty P, Vander Salm T, Cutler B
J Thorac Cardiovasc Surg. 1982 Sep;84(3):387-91.
The survival of autologous red blood cells (RBCs) collected during operation from the surgical field and processed immediately by the Haemonetics Cell Saver was compared to the survival of autologous nonprocessed RBCs obtained by venipuncture in nine patients undergoing reconstructive vascular operations and four patients undergoing coronary artery bypass. A double isotope technique (Cr-51 and In-111) was used to determine the survival of the different cell populations. Seven patients undergoing coronary artery bypass served as controls to characterize the isotopes by labeling the same population of RBCs with each radionuclide. Comparison of the data in all groups failed to show any significant difference in either the immediate or long-term survival between autotransfused (Cell Saver--processed) blood and nonprocessed RBCs. This study indicates that shed blood collected and processed at operation with the Haemonetics Cell Saver can be autotransfused and that the in vivo survival of these cells is not significantly different from the survival of nonprocessed blood.
对9例行血管重建手术和4例行冠状动脉搭桥手术的患者，比较术中从手术野收集并立即由血液回收机处理的自体红细胞（RBC）的存活情况，与通过静脉穿刺获得的未经处理的自体RBC的存活情况。采用双同位素技术（铬-51和铟-111）来确定不同细胞群体的存活情况。7例行冠状动脉搭桥手术的患者作为对照，通过用每种放射性核素标记同一群体的RBC来表征同位素。对所有组的数据进行比较后发现，自体输血（血液回收机处理）的血液和未经处理的RBC在即时或长期存活方面均无显著差异。本研究表明，术中用血液回收机收集和处理的 shed blood 可进行自体输血，且这些细胞在体内的存活情况与未经处理的血液的存活情况无显著差异。
