Bertrand B, Degen A
Acta Otorhinolaryngol Belg. 1984;38(3):337-44.
The authors report three cases of patients suffering from repeated infection of the upper and lower respiratory tracts. Mucociliary clearance, measured in the nasal fossae by coloured indicators, is reduced. Both transmission and scanning electronic ultramicroscopic study of the vibratile cilia show a morphological malformation of "hockey-stick" appearance, while the structure of the exonemal microtubular apparatus is normal and complete. This morphological ciliary abnormality is held to be responsible for the respiratory pathology in the three cases observed.
作者报告了3例反复发生上、下呼吸道感染的患者。通过彩色指示剂在鼻窝测量的黏液纤毛清除功能降低。对摆动纤毛进行的透射电子显微镜和扫描电子显微镜研究均显示出呈“曲棍球棒”外观的形态畸形,而轴丝微管结构正常且完整。这种纤毛形态异常被认为是所观察到的3例患者出现呼吸道病变的原因。