Attfield M, Reger R, Glenn R
Am J Ind Med. 1984;6(6):407-15. doi: 10.1002/ajim.4700060604.
Chest radiographs, taken at a 9-year interval for 1,261 U.S. coal miners, were read for pneumoconiosis side-by-side by six readers in a controlled trial. Incidence and progression of small, rounded opacities were consistent with levels predicted from dose-response curves developed by the British Pneumoconiosis Field Research interpolated at a concentration derived from U.S. compliance levels mandated over the last 9 years. The results imply that the level of pneumoconiosis in U.S. miners is being reduced through application of the current 2 mg/m3 standard. The long developmental period for pneumoconiosis necessitates that further study be undertaken to verify this finding and to determine whether 2 mg/m3 is an appropriate regulatory dust level for the prevention of category 2 or greater simple pneumoconiosis over a 35-year period.
在一项对照试验中，6名阅片者对1261名美国煤矿工人间隔9年拍摄的胸部X光片进行了尘肺病阅片。小圆形阴影的发病率和进展情况与根据英国尘肺病现场研究得出的剂量反应曲线预测的水平一致，该曲线是根据过去9年美国规定的合规浓度进行插值得到的。结果表明，通过应用当前2毫克/立方米的标准，美国矿工的尘肺病水平正在降低。尘肺病的发展周期较长，因此有必要进一步开展研究，以验证这一发现，并确定2毫克/立方米是否是35年内预防2级或更严重单纯性尘肺病的合适监管粉尘水平。
