Kester P A
Arch Sex Behav. 1984 Oct;13(5):441-55. doi: 10.1007/BF01541429.
The study was designed to determine whether exogenous prenatal exposure to 17 alpha-hydroxyprogesterone caproate (Delalutin) affects male recreational interests in boyhood and adolescence and male psychosexual development and whether total dosage, duration, and time of exposure has an effect on the previously mentioned variables. Subjects included 25 prenatally Delalutin-exposed males and 25 closely matched unexposed males. Subjects were administered the Bender Visual-Motor Gestalt Test, the Draw-a-Person Test, the Rosenzweig Picture-Frustration Study for Adolescents, the Embedded Figures Test, and the Forer Structured-Sentence Completion Test. Also, both subjects and their mothers were interviewed. Analysis of the data utilized raters to score subjective test instruments. Statistical analysis was conducted by t test, sign test, and multiple correlation. Only one significant difference was evident. Delalutin-exposed subjects spend significantly more time in the sedentary pursuit of watching television. However, there was no significant difference in their expressed interest in watching television or the type of television programs selected. The total dosage, duration, and period of gestation of drug administration had no significant effect in altering the findings. But a subtle difference was observed when the Delalutin regimen was not constant and when there was an interaction between psychological variables and the drug regimen.
该研究旨在确定孕期外源性接触己酸17α-羟孕酮（羟孕酮己酸酯）是否会影响男性在童年和青春期的娱乐兴趣以及男性的性心理发育，以及总剂量、持续时间和接触时间是否会对上述变量产生影响。研究对象包括25名孕期接触过羟孕酮己酸酯的男性和25名匹配度较高的未接触过该物质的男性。研究对象接受了本德尔视觉运动完形测验、画人测验、青少年罗森茨韦格图片挫折研究、镶嵌图形测验和福尔结构化句子完成测验。此外，还对研究对象及其母亲进行了访谈。数据分析由评分者对主观测试工具进行评分。采用t检验、符号检验和多重相关分析进行统计分析。仅发现一个显著差异。接触过羟孕酮己酸酯的研究对象在久坐看电视上花费的时间明显更多。然而，他们对看电视的兴趣表达或所选电视节目的类型并无显著差异。药物给药的总剂量、持续时间和妊娠期对研究结果没有显著影响。但是，当羟孕酮己酸酯给药方案不固定且心理变量与药物方案之间存在相互作用时，观察到了细微的差异。
