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食蚊鱼科鱼类孔雀鱼(Poecilia reticulatus)心脏的衰老变化。

Aging changes in the heart of a poeciliid fish, the guppy Poecilia reticulatus.

作者信息

Woodhead A D

出版信息

Exp Gerontol. 1984;19(6):383-91. doi: 10.1016/0531-5565(84)90048-2.

DOI:10.1016/0531-5565(84)90048-2
PMID:6519210
Abstract

Histological surveys of the hearts of guppies Poecilia reticulatus throughout their lifespan showed no aging changes until the fish were three years old. In younger fishes the hearts were healthy, even in three individuals with "wasting" disease, where there was considerable loss of muscle throughout the body. There was a loss of muscle fibers in the ventricle in old fish, and deposition of collagen in the bulbus arteriosus. Guppies of three years and older also had a marked accumulation of melanomacrophages in the atrium. It seems unlikely that degeneration of the heart is involved in mortality of guppies in the wild.

摘要

对孔雀鱼(Poecilia reticulatus)一生中心脏的组织学调查显示,直到鱼三岁时都没有衰老变化。在较年轻的鱼中,心脏是健康的,即使是在三条患有“消瘦”疾病的鱼中,它们全身肌肉有相当程度的损失。老年鱼的心室中出现肌纤维损失,动脉球中有胶原蛋白沉积。三岁及以上的孔雀鱼心房中也有明显的黑素巨噬细胞积累。心脏退化似乎不太可能是野生孔雀鱼死亡的原因。

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