Panizzon R, Brüngger H, Vogel A
Hautarzt. 1984 Nov;35(11):578-84.
The study presented here is based on the clinicopathological and electron microscopical analysis of 39 patients with Becker's nevus (BN). The clinical picture is variable and we therefore suggest the following three types be distinguished: (1) the melanotic type, (2) the hypertrichotic type, and (3) the mixed type. In BN the sensitivity reaction was often diminished. Among the skin eruptions other than BN, we would like to stress that 12% of our patients showed a malignant melanoma. Histopathology concerns both epidermal and dermal structures. The electron microscopic findings corresponded well with those by light microscopy. As far as we know, the changes in collagen fibrils are demonstrated for the first time in this study.
本文所呈现的研究基于对39例贝克痣(BN)患者的临床病理及电子显微镜分析。临床表现多样,因此我们建议区分以下三种类型:(1)色素沉着型,(2)多毛型,(3)混合型。在BN中,感觉反应常减退。在除BN之外的皮肤疹中,我们想强调的是,我们的患者中有12%表现为恶性黑色素瘤。组织病理学涉及表皮和真皮结构。电子显微镜检查结果与光学显微镜检查结果非常吻合。据我们所知,本研究首次证实了胶原纤维的变化。