Murphy J P, Holder T M, Ashcraft K W, Sharp R J, Goodwin C D, Amoury R A
J Pediatr Surg. 1984 Dec;19(6):642-8. doi: 10.1016/s0022-3468(84)80347-4.
Ureteropelvic junction (UPJ) obstruction is a common cause of hydronephrosis in infants. Newborns with severe obstruction often have marked improvement following correction; therefore early diagnosis and operation is important. From 1973 to 1983, 21 patients were operated on for UPJ obstruction diagnosed under 6 weeks of age. Six patients (29%) had antenatal ultrasonographic diagnosis. The remaining patients were diagnosed by IVP or radionuclide scan for palpable renal enlargment or for associated anomalies. Seventeen had unilateral and four had bilateral obstruction. Twenty-three pyeloplasties, one primary nephrectomy, and one cutaneous pyelostomy with subsequent nephrectomy were done. All pyeloplasties were dismembered, with tailoring of the renal pelvis. Postoperative renal function was followed with radionuclide scan or IVP. Postoperative complications included a single urinary tract infection in three patients and two bowel obstructions. One early postoperative death occurred in an infant with bilateral obstruction who developed congestive heart failure secondary to severe uncontrollable hypertension. There were two other unrelated late deaths. Documented functional improvement with minimal complications follow unilateral or simultaneous bilateral pyeloplasty in newborns with UPJ obstruction.
肾盂输尿管连接部(UPJ)梗阻是婴儿肾积水的常见原因。重度梗阻的新生儿在矫正后通常有明显改善;因此,早期诊断和手术很重要。1973年至1983年,21例6周龄以下诊断为UPJ梗阻的患者接受了手术。6例(29%)有产前超声诊断。其余患者通过静脉肾盂造影(IVP)或放射性核素扫描诊断,原因是可触及肾脏增大或存在相关异常。17例为单侧梗阻,4例为双侧梗阻。进行了23例肾盂成形术、1例一期肾切除术和1例皮肤肾盂造瘘术及随后的肾切除术。所有肾盂成形术均为离断性,对肾盂进行了修整。术后通过放射性核素扫描或IVP跟踪肾功能。术后并发症包括3例患者发生1次尿路感染和2例肠梗阻。1例双侧梗阻的婴儿术后早期死亡,死于严重无法控制的高血压继发的充血性心力衰竭。还有另外2例无关的晚期死亡。有记录显示,对于患有UPJ梗阻的新生儿,单侧或同时双侧肾盂成形术后功能改善且并发症最少。