Kudriakova S V, Suntsov Iu I, Slavina L S, Mazovetskii A G
Kardiologiia. 1984 Nov;24(11):40-3.
A hundred males aged 40-69 years receiving treatment at the Institute of Experimental Endocrinology and Hormone Chemistry for type I and II diabetes mellitus were examined. Thirty-eight patients had coronary heart disease (CHD). The diagnosis of CHD was based on the data of the WHO Cardiological Questionnaire and the presence of ECG changes corresponding to the categories of the Minnesota Code 1-1,2,7; 4-1,2 and 5-1,2 (without 3-1,3). The blood levels of total cholesterol (CS), triglycerides (TG), high density lipoprotein cholesterol (HDLC) and the atherogenicity coefficient (AC) were determined in all patients. The results of the study showed that males with diabetes mellitus irrespective of its type or the presence of CHD had significantly higher mean values of total CS, TG and AC than in control. The mean levels of HDLC in males with type I diabetes mellitus without CHD did not differ from those in normal subjects whereas the level of HDLC in patients with type II diabetes mellitus was lowered. The patients with CHD showed a significant decrease in HDLC in both type I and II diabetes. The highest mean values of TG, AC and the lowest levels of HDLC were characteristic of the males with type II diabetes mellitus and CHD.
对在实验性内分泌学与激素化学研究所接受 I 型和 II 型糖尿病治疗的 100 名年龄在 40 - 69 岁的男性进行了检查。38 名患者患有冠心病（CHD）。冠心病的诊断基于世界卫生组织心脏病学调查问卷的数据以及心电图变化符合明尼苏达编码 1 - 1、2、7；4 - 1、2 和 5 - 1、2（不包括 3 - 1、3）的类别。测定了所有患者的总胆固醇（CS）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDLC）水平和致动脉粥样硬化系数（AC）。研究结果表明，无论糖尿病类型或是否患有冠心病，糖尿病男性的总 CS、TG 和 AC 的平均值均显著高于对照组。无冠心病的 I 型糖尿病男性的 HDLC 平均水平与正常受试者无异，而 II 型糖尿病患者的 HDLC 水平降低。患有冠心病的患者在 I 型和 II 型糖尿病中 HDLC 均显著降低。TG、AC 的平均值最高且 HDLC 水平最低是 II 型糖尿病合并冠心病男性的特征。
