von Scheel J, Golde G
Laryngol Rhinol Otol (Stuttg). 1984 Nov;63(11):575-9.
The complex theoretical background of intra-arterial (i.a.) tumour therapy induced the installation of a computer assisted model based on the use of 7 variables, the most important factors being the blood flow of the infused organ and the clearance of the drug, as well as the tissue binding of the drug. Various relevant conditions of i.a. infusion are represented by simple but typical diagrams allowing quick orientation on the principles governing i.a. infusion even for those who are not very familiar with the theoretical background of i.a. infusion. The model represents an improvement in the individual planning of effective i.a. chemotherapy.
动脉内肿瘤治疗复杂的理论背景促使建立了一个基于7个变量的计算机辅助模型,其中最重要的因素是被灌注器官的血流、药物清除率以及药物的组织结合情况。动脉内灌注的各种相关条件通过简单但典型的图表呈现,即使对于那些不太熟悉动脉内灌注理论背景的人来说,也能快速了解动脉内灌注的原理。该模型代表了有效动脉内化疗个体化规划方面的一种改进。