Kobayashi S, Oka N, Mitsuhashi H, Suda S, Sato A, Shinohara Y, Watanabe Y, Aoki T, Yamaura A, Makino H
No Shinkei Geka. 1984 Dec;12(13):1477-84.
Forty-two dynamic CT studies were performed on 27 patients with cerebral infarction (11 to 75 years of age), and perfusion patterns of low density areas on plain CT were evaluated. The initial studies were performed 1.5 hours to 60 days after acute onset. In 14 patients, repeat studies were carried out to know how the perfusion pattern changes with time. All scannings were done on the level which includes anterior horns and trigones of lateral ventricle, thalamus, and internal capsules. CT scanners used were SIEMENS SOMATOM 2 and GE CT/T 8800. Procedures were as follows: 65% amidotrizomeglumin (1 ml/kg) was injected over 5 seconds through 18G needle placed in a antecubital vein. Injection of the contrast media was started with initiation of the second scanning. Totally 8 and 10 serial scans were performed, in SOMATOM 2 and CT/T 8800 respectively. Perfusion pattern is evaluated by comparing two time-density curves obtained from low density area on plain CT and the same region of contralateral side. The following results were obtained. The perfusion pattern in the low density area on plain CT varies among patients at any periods after onset, ranging from absent perfusion pattern to hyperfusion pattern. No consistent perfusion pattern was obtained at any given time after onset. Repeat dynamic CT revealed that the perfusion pattern in the low density area changed with time variously. The perfusion pattern or change of perfusion pattern did not correlate with outcome of the patient.(ABSTRACT TRUNCATED AT 250 WORDS)
对27例脑梗死患者(年龄11至75岁)进行了42次动态CT研究,评估了平扫CT上低密度区的灌注模式。初始研究在急性发病后1.5小时至60天进行。14例患者进行了重复研究,以了解灌注模式如何随时间变化。所有扫描均在包括侧脑室前角和三角区、丘脑及内囊的层面进行。使用的CT扫描仪为西门子SOMATOM 2和GE CT/T 8800。操作步骤如下:通过置于肘前静脉的18G针头在5秒内注入65%泛影葡胺(1 ml/kg)。在开始第二次扫描时开始注射造影剂。在SOMATOM 2和CT/T 8800上分别进行了8次和10次连续扫描。通过比较平扫CT上低密度区和对侧相同区域获得的两条时间-密度曲线来评估灌注模式。获得了以下结果。平扫CT上低密度区的灌注模式在发病后的任何时期患者之间都有所不同,从无灌注模式到高灌注模式不等。在发病后的任何特定时间都未获得一致的灌注模式。重复动态CT显示,低密度区的灌注模式随时间变化各异。灌注模式或灌注模式的变化与患者的预后无关。(摘要截短至250字)