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[幕下少突胶质细胞瘤:一例报告]

[Infratentorial oligodendroglioma: report of a case].

作者信息

Kitoh A, Itoh Y, Banno T

出版信息

No Shinkei Geka. 1984 Dec;12(13):1523-7.

PMID:6521840
Abstract

Oligodendroglioma occurs primarily in the cerebral hemisphere in adult. A rare case of oligodendroglioma in the cerebellum is presented, and previous reported cases were reviewed. A thirty-one year old female was admitted to our service only with headache. CT scan demonstrated a low density mass in the vermis of the cerebellum which was not enhanced. Bilateral vertebral angiography showed an avascular mass in the vermis. The preoperative diagnosis was astrocytoma or ependymoma, and a suboccipital craniotomy was performed. The tumor which was soft, yellowish gray and well-circumscribed, was developed from the vermis and extended into the cisterna magna. The tumor which size was approximately 3 X 4 X 5 cm. Microscopically the specimen showed round, darkly stained nuclei and clear perinuclear cytoplasmic halos. Moreover, the immunoperoxidase method testified the absence of glial fibrillary acidic protein in the tumor cells. The pathological diagnosis was oligodendroglioma. Post-operatively the patient was doing well without any complications. There was no clinical nor CT evidence of tumor recurrence forty months after resection. The 11 reported cases of infratentorial oligodendroglioma including ours were analyzed and the following conclusion was obtained. Infratentorial oligodendroglioma occurs in the younger age group. The tumor has special tendency to form cyst. Frequency of calcification is low. Prognosis is good if the tumor is resected in early stage. Pre-operatively, however, it was difficult to differentiate oligodendroglioma from astrocytoma.

摘要

少突胶质细胞瘤主要发生于成人的大脑半球。本文报告了1例罕见的小脑少突胶质细胞瘤,并复习了既往报道的病例。1名31岁女性因头痛入院。CT扫描显示小脑蚓部有一低密度肿块,无强化。双侧椎动脉血管造影显示蚓部有一无血管肿块。术前诊断为星形细胞瘤或室管膜瘤,遂行枕下开颅手术。肿瘤质地软,呈黄灰色,边界清楚,起源于蚓部并延伸至枕大池。肿瘤大小约为3×4×5cm。显微镜下标本显示细胞核圆形、深染,核周胞质晕清晰。此外,免疫过氧化物酶法证实肿瘤细胞中无胶质纤维酸性蛋白。病理诊断为少突胶质细胞瘤。术后患者恢复良好,无任何并发症。切除术后40个月,无临床及CT证据提示肿瘤复发。对包括本文病例在内的11例幕下少突胶质细胞瘤报道病例进行分析,得出以下结论。幕下少突胶质细胞瘤发生于较年轻的年龄组。肿瘤有形成囊肿的特殊倾向。钙化频率低。如果肿瘤早期切除,预后良好。然而,术前很难将少突胶质细胞瘤与星形细胞瘤区分开来。

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