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成人呼吸窘迫综合征(休克肺)的诊断形态测定法

Diagnostic morphometry of the adult respiratory distress syndrome (shock lung).

作者信息

Riede U N, Shah I

出版信息

Pathol Res Pract. 1984 Nov;179(2):204-6. doi: 10.1016/S0344-0338(84)80129-6.

Abstract

In the pathogenesis of "shock lung", the morphometric analysis allows us to determine the "point of no return" when the exudative alveolitis turns into the life-threatening sclerosing form. In addition, we found that this "point of no return" is reached much earlier in septic than in traumatic shock. Our studies confirm that the term "shock lung" should not be simply substituted for "respiratory lung". Based on our morphometric methods, we conclude that shock-induced pulmonary fibrosis differs with regard to its functional pathogenesis from the non-shock-induced type of fibrosis.

摘要

在“休克肺”的发病机制中,形态计量分析使我们能够确定渗出性肺泡炎转变为危及生命的硬化形式时的“不可逆点”。此外,我们发现脓毒性休克比创伤性休克更早达到这一“不可逆点”。我们的研究证实,“休克肺”一词不应简单地用“呼吸窘迫综合征”来替代。基于我们的形态计量学方法,我们得出结论,休克诱导的肺纤维化在功能发病机制上与非休克诱导的纤维化类型不同。

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