Gmerek D E, Cowan A
Regul Pept. 1984 Nov;9(4):299-304. doi: 10.1016/0167-0115(84)90082-x.
Centrally administered bombesin (0.1-3.5 micrograms, i.c.v.) inhibits gastrointestinal transit of a charcoal meal in a dose-related manner in rats. The roles of pituitary and adrenal glands in the mediation of this effect were assessed. The inhibition of gastrointestinal transit associated with bombesin (0.5 microgram, i.c.v.) was prevented by either hypophysectomy or adrenalectomy. Bombesin-induced inhibition of gastrointestinal transit is therefore mediated through the pituitary-adrenal axis. This is in contrast to bombesin-induced scratching and inhibition of gastric acid secretion which are not markedly influenced by either hypophysectomy or adrenalectomy.
脑室内注射蛙皮素（0.1 - 3.5微克）可剂量依赖性地抑制大鼠肠道内炭末的推进。研究评估了垂体和肾上腺在介导此效应中的作用。垂体切除或肾上腺切除均可阻止蛙皮素（0.5微克，脑室内注射）对肠道推进的抑制作用。因此，蛙皮素诱导的肠道推进抑制是通过垂体 - 肾上腺轴介导的。这与蛙皮素诱导的搔抓行为及胃酸分泌抑制不同，垂体切除或肾上腺切除对二者无明显影响。
