Manelis G, Shasha S M, Manelis J, Suprun H, Robinson E
Oncology. 1978;35(2):83-6. doi: 10.1159/000225261.
The case of a 47-year-old white female patient has been described with malignant melanoma that started as a node on her right ankle twelve years ago and regressed spontaneously. During the last two years of her life, dissemination of the melanoma appeared in the form of subcutaneous nodes, which regressed spontaneously in successive crops. In the course of her disease there was evidence of distant metastases to the brain. Spontaneous regression seems to have been enhanced by immunotherapy, when most of the metastases had regressed, including those in the brain.
一名47岁白人女性患者的病例被报道，其恶性黑色素瘤始于12年前右踝部的一个结节，后自发消退。在其生命的最后两年，黑色素瘤以皮下结节的形式出现播散，并相继分批自发消退。在疾病过程中，有远处转移至脑的证据。当大多数转移灶包括脑内转移灶消退时，免疫治疗似乎增强了自发消退。
