Garrel S, Barret L, Maynard R, Brun-Buisson N, Josse J
Rev Electroencephalogr Neurophysiol Clin. 1984 Nov;14(2):125-31. doi: 10.1016/s0370-4475(84)80017-9.
24 deep toxic comas with respiratory assistance were studied by brain-stem reflex and BAEP. Laboratory analysis showed several simultaneous toxics (phenobarbital, benzodiazepines, tricyclic antidepressants...). Three groups of patients were defined: Twelve patients with normal BAEP and with relatively preserved brain-stem reflex (oculocephalic and oculovestibular are often disturbed but photomotor is present). Eleven patients with delayed BAEP and with more disturbed brain-stem reflex (photomotor is missing 3 times). In 2 cases (one of which is mentioned above in group B) brain-stem reflex and BAEP disappear and these patients die. Cerebral anoxia is associated here with toxics. Causes of delayed latencies (group B) are discussed (hypothermia, toxics). BAEP seems important in diagnosis and prognosis of toxic coma.
通过脑干反射和脑干听觉诱发电位(BAEP)对24例接受呼吸辅助的深度中毒性昏迷患者进行了研究。实验室分析显示存在几种同时中毒的情况(苯巴比妥、苯二氮卓类、三环类抗抑郁药……)。确定了三组患者:12例BAEP正常且脑干反射相对保留的患者(眼头反射和眼前庭反射常受干扰,但光反射存在)。11例BAEP延迟且脑干反射受更严重干扰的患者(光反射缺失3次)。在2例患者中(其中1例在B组中提及),脑干反射和BAEP消失,这些患者死亡。此处脑缺氧与中毒有关。讨论了潜伏期延迟(B组)的原因(体温过低、中毒)。BAEP在中毒性昏迷的诊断和预后中似乎很重要。