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[慢性缺血性心脏病合并左心室衰竭患者的外周氧合与灌注]

[Peripheral oxygenation and perfusion in patients with chronic ischemic heart disease complicated by left-ventricular failure].

作者信息

Tiukalova L I, Shteĭngard Iu N

出版信息

Ter Arkh. 1984;56(12):25-7.

PMID:6523407
Abstract

Examination of 33 normal subjects and 91 patients with coronary heart disease (CHD) ascertained that during CHD (diffuse atherosclerotic and postinfarction cardiosclerosis) without clinically marked heart insufficiency, oxygen tension in the arterialized capillary blood and subcutaneous fat of the forearm was normal in the overwhelming majority of cases. Only some of the patients manifested negligible arterial hypoxemia and/or tissue hypoxia. Left ventricular failure was always accompanied by arterial hypoxemia and tissue hypoxia the degree of which was proportional to the gravity of heart insufficiency. In isolated left ventricular failure without congestion in the greater circulation, CHD patients demonstrated abnormal peripheral circulation and tissue perfusion. In particular, the distensibility of the forearm veins was decreased by 43-50%, their capacity was reduced by 28-43%, and the volumetric velocity of the peripheral blood flow in this area was lessened by 34-58%.

摘要

对33名正常受试者和91名冠心病(CHD)患者的检查确定,在无明显临床心力衰竭的冠心病(弥漫性动脉粥样硬化和心肌梗死后心肌硬化)期间,绝大多数病例中,前臂动脉化毛细血管血和皮下脂肪中的氧张力正常。只有部分患者表现出轻微的动脉低氧血症和/或组织缺氧。左心衰竭总是伴有动脉低氧血症和组织缺氧,其程度与心力衰竭的严重程度成正比。在孤立性左心衰竭且无大循环淤血的情况下,冠心病患者表现出外周循环和组织灌注异常。特别是,前臂静脉的扩张性降低了43% - 50%,其容量减少了28% - 43%,该区域外周血流的容积速度降低了34% - 58%。

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