Kohno H, Furuhashi N, Fukaya T, Shinkawa O, Tachibana Y, Suzuki M
Tohoku J Exp Med. 1984 Nov;144(3):299-304. doi: 10.1620/tjem.144.299.
We measured maternal venous (MV), umbilical arterial (UA) and umbilical venous (UV) cortisol levels in 180 term pregnancies to investigate the changes of these hormone levels in the cases of fetal distress and neonatal asphyxia. The cortisol levels in UA and UV blood in the fetal distress group were significantly higher than those in the non-fetal distress group among spontaneous vaginal delivery cases. There were significant positive correlations among the cortisol levels in MV and UA, MV and UV, and UA and UV blood, respectively. These data suggest that in the case of fetal distress or neonatal asphyxia, mother and fetus have responded independently to the stress of delivery, and that maternal cortisol might not strongly affect the fetal cortisol secretion.
我们检测了180例足月妊娠孕妇的母血静脉血(MV)、脐动脉血(UA)和脐静脉血(UV)中的皮质醇水平,以研究胎儿窘迫和新生儿窒息情况下这些激素水平的变化。在自然阴道分娩的病例中,胎儿窘迫组的脐动脉血和脐静脉血中的皮质醇水平显著高于非胎儿窘迫组。母血静脉血与脐动脉血、母血静脉血与脐静脉血、脐动脉血与脐静脉血中的皮质醇水平之间分别存在显著的正相关。这些数据表明,在胎儿窘迫或新生儿窒息的情况下,母亲和胎儿对分娩应激有独立的反应,且母体皮质醇可能不会强烈影响胎儿皮质醇的分泌。