Bouissou H, Alzieu J, Pieraggi M T, Julian M
Paroi Arterielle. 1978 Jan-Feb;4(2):135-47.
Thirty-five dissecting aneurisms of the aorta (D.A.). have been microscopically and ultramicroscopically examined. These data have been compared to those obtained from personal experiences on human aorta aging, as well as from Beta Aminopropionitrile treated rats. The authors conceive D.A. as a non-obligatory complication of a precocious and intense medianecrosis of the aortic wall, particularly characterized by a mucous imbibition and a loss elastic laminae. This medianecrosis is identical in dysplasic D.A. (Martan's syndrome for example) and in acquired D.A. (rapid aging or arteriosclerosis). The simultaneous occurence of a medianecrosis and conditions triggering tunica intima rupture, with blood afflux in the necrotic zone are undoubtedly rare. This explains the small number of observed D.A. in comparison to the large number of aortas with accentuated medial lesions.
对35例主动脉夹层动脉瘤（D.A.）进行了显微镜和超显微镜检查。这些数据已与从人体主动脉老化的个人经验以及β-氨基丙腈处理的大鼠中获得的数据进行了比较。作者认为D.A.是主动脉壁早熟和严重中层坏死的一种非必然并发症，其特别特征为黏液浸润和弹性层丧失。这种中层坏死在发育异常的D.A.（例如马凡综合征）和后天性D.A.（快速老化或动脉硬化）中是相同的。中层坏死与触发内膜破裂并使血液流入坏死区的情况同时发生无疑是罕见的。这解释了与大量有明显中层病变的主动脉相比，观察到的D.A.数量较少的原因。
