Mueller R L, Hagel H J, Greim G, Ruppin H, Domschke W
Zentralbl Bakteriol Mikrobiol Hyg B. 1984 Oct;179(5):381-96.
The fasting gastric secretion was analysed both bacteriologically and chemically in 15 young, voluntary test subjects with histories of a healthy stomach and physiological gastric secretion tests (Basal Acid Output, Peak Acid Output) made at regular intervals of two and 4 weeks over a period of three and six months. Two thirds of the persons studied showed during the entire period of examination the same pH values with tolerable variations and, as a result, the same order of magnitude for the total germ count, the colony count of the nitrite-forming bacteria and for the NO2- concentration. From this the conclusion can be drawn that, depending on the acidity of the individual stomach, there is an autonomous bacterial flora, which repeated examinations have shown to remain unaltered in quality and quantity. It was only in one third of the test persons that major variations of the pH values could be recorded occasionally. This, however, invariably led to corresponding changes in the bacteriological and chemical parameters. For requirements imposed by preventive medicine and hygiene, in future greater attention must be paid to the bacterial flora of the intact stomach, while making due allowance for the endogenous nitrite formation.
对15名年轻的自愿受试对象的空腹胃液进行了细菌学和化学分析，这些受试对象有健康胃部病史，并在三到六个月的时间里每隔两周和四周定期进行生理胃液分泌测试（基础酸排出量、最大酸排出量）。三分之二的受试人员在整个检查期间显示出相同的pH值，变化在可容忍范围内，因此，总细菌计数、亚硝酸盐形成菌的菌落计数以及NO2-浓度的数量级相同。由此可以得出结论，根据个体胃部的酸度，存在一种自主细菌群落，多次检查表明其质量和数量保持不变。只有三分之一的受试人员偶尔会记录到pH值的重大变化。然而，这总是导致细菌学和化学参数的相应变化。出于预防医学和卫生学的要求，今后在充分考虑内源性亚硝酸盐形成的同时，必须更加关注完整胃部的细菌群落。
