Pyykkö I, Dahlen A I, Schalén L, Hindfelt B
Acta Otolaryngol. 1984 Nov-Dec;98(5-6):485-9.
Saccades, smooth pursuit and angular acceleration induced nystagmus were analysed quantitatively in 10 patients with speech dyspraxia. The saccades were less accurate, had a prolonged reaction time and showed a tendency to reduced peak velocity, though only contralateral to the lesion. Smooth pursuit was imparied, with a reduction in maximum velocity gain. The vestibular responses tended to be hyperactive, indicating facilitated brain-stem reflexes. The findings show that a lesion in the frontal eye field can produce various oculomotor disturbances, in which the triggering of eye movements and their control, and pacing of the various movement sequences are disturbed. In addition, anticipation of a movement pattern requiring volition may be greatly impaired.
对10例言语失用症患者的扫视、平稳跟踪和角加速度诱发的眼球震颤进行了定量分析。扫视准确性较低，反应时间延长，且仅在病变对侧有峰值速度降低的趋势。平稳跟踪受损，最大速度增益降低。前庭反应往往亢进，表明脑干反射增强。研究结果表明，额叶眼区病变可产生各种眼球运动障碍，其中眼球运动的触发及其控制以及各种运动序列的起搏均受到干扰。此外，对需要意志的运动模式的预期可能会严重受损。
