Sujov P, Kellerman L, Zeltzer M, Hochberg Z
Acta Paediatr Scand. 1984 Nov;73(6):722-6. doi: 10.1111/j.1651-2227.1984.tb17765.x.
The purpose of the present study was to determine the normal relationship of urine and plasma osmolality in pre-term and full-term infants. Twenty-nine full-term and 35 pre-term babies were studied during the first week of life. Random simultaneous urine and plasma samples were measured for osmolality. Statistical analysis defined the normal relationship of plasma to urine osmolality. This suggests an osmotic threshold of 282 mOsm/kg and 291 mOsm/kg for full-term and pre-term babies, respectively. These values are different from the 285-290 mOsm/kg of adolescents and adults. The nomograms provided may serve as a useful aid in the bedside diagnosis of dysfunctional secretion of vasopressin.
本研究的目的是确定早产儿和足月儿尿液与血浆渗透压的正常关系。对29名足月儿和35名早产儿在出生后第一周进行了研究。随机同时采集尿液和血浆样本测量渗透压。统计分析确定了血浆与尿液渗透压的正常关系。这表明足月儿和早产儿的渗透阈值分别为282 mOsm/kg和291 mOsm/kg。这些值与青少年和成年人的285 - 290 mOsm/kg不同。提供的列线图可能有助于床边诊断抗利尿激素分泌异常。