Asano S, Tsuchiyama M, Shimoe S, Sagawa S
Hinyokika Kiyo. 1984 Sep;30(9):1285-92.
A case of bilateral testicular germ cell tumors of different cell types and maturation in the metastatic region is described. A 42-year-old man with bilateral testicular swelling visited our clinic. Bilateral high orchiectomy was performed. Subsequent histological examination revealed seminoma and embryonal carcinoma in the right testis and seminoma and mature teratoma in the left. Then bilateral retroperitoneal lymphadenectomy was performed and 7 metastatic regions were found in the para-aortic lymph nodes. One of these revealed histopathologically a mature teratoma containing cartilage constituents. After the operation, multiple drug treatment with Cis-DDP, vinblastine and pepleomycin was started. The patient has been in complete remission for about 1.5 year. In addition, we reviewed the literature about bilateral testicular germ cell tumors and maturation in the metastatic region.
本文描述了一例在转移区域出现不同细胞类型和成熟度的双侧睾丸生殖细胞肿瘤病例。一名42岁双侧睾丸肿大的男性前来我院就诊。实施了双侧高位睾丸切除术。随后的组织学检查显示,右侧睾丸为精原细胞瘤和胚胎癌,左侧为精原细胞瘤和成熟畸胎瘤。接着进行了双侧腹膜后淋巴结清扫术,在主动脉旁淋巴结中发现了7个转移区域。其中一个区域在组织病理学上显示为含有软骨成分的成熟畸胎瘤。术后开始使用顺铂、长春碱和博来霉素进行多药治疗。该患者已完全缓解约1.5年。此外,我们还回顾了关于双侧睾丸生殖细胞肿瘤及转移区域成熟度的文献。