Diioria D P, Nadakavukaren M J
Anat Rec. 1984 Nov;210(3):449-52. doi: 10.1002/ar.1092100305.
Harderian gland ultrastructure was examined at biweeky intervals for 16 weeks after either pinealectomy or sham-operation of male and female hamsters kept in 1L:23D and 14L:10D photoperiods. Female characteristics such as membrane formations and extensive smooth endoplasmic reticulum appeared in the males kept under short photoperiod conditions. Similarly, male characteristics such as the tubular clusters appeared in the glands of females kept in the short photoperiod. When male and female hamsters were pinealectomized and exposed to the short photoperiod, the glands in each sex retained the characteristics typical of that sex. Atrophy of the testes and uteri was also observed in the sham-operated hamsters maintained under short photoperiods, but not in the pinealectomized animals. The changes observed in the Harderian glands and reproductive organs of hamsters kept in the short photoperiod were not observed in the hamsters maintained in the long photoperiod. The photoperiod-induced ultrastructural changes in the hamster Harderian glands are most likely due to changes in hormonal levels brought about by the regression of reproductive organs and can be prevented by pinealectomy.
在1L:23D和14L:10D光周期条件下，对雄性和雌性仓鼠进行松果体切除或假手术后，每两周检查一次哈德氏腺的超微结构，持续16周。在短光周期条件下饲养的雄性仓鼠出现了诸如膜形成和广泛的光滑内质网等雌性特征。同样，在短光周期条件下饲养的雌性仓鼠的腺体中出现了诸如管状簇等雄性特征。当雄性和雌性仓鼠被切除松果体并暴露于短光周期时，每种性别的腺体都保留了该性别的典型特征。在短光周期下饲养的假手术仓鼠中也观察到睾丸和子宫萎缩，但在松果体切除的动物中未观察到。在长光周期下饲养的仓鼠中未观察到短光周期下饲养的仓鼠哈德氏腺和生殖器官中观察到的变化。仓鼠哈德氏腺中光周期诱导的超微结构变化很可能是由于生殖器官退化导致的激素水平变化引起的，并且可以通过松果体切除来预防。
