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诱导感染鹿丝状线虫后家兔血清蛋白变化及其与抗体产生的相关性

Serum protein changes and their correlation with antibody production in rabbits following induced Setaria cervi infection.

作者信息

Khatoon H, Baqui A, Ansari J A

出版信息

Angew Parasitol. 1984 Nov;25(4):203-7.

PMID:6524705
Abstract

The sera obtained from normal control and Setaria cervi infected rabbits were analysed weekly both qualitatively and quantitatively. Electrophoretic studies as well as biochemical estimation reveal an increase in total protein and globulin and a decrease in albumin level. The changes were more marked in the third week, followed by a declining phase reaching an almost normal level by the sixth week. The increased globulin level analysed electrophoretically also coincided with the appearance of 2 precipitin arcs in immunoelectrophoretic analysis indicating a correlation between antibody production and hyperglobulinaemia.

摘要

每周对从正常对照兔和感染鹿丝状线虫的兔获得的血清进行定性和定量分析。电泳研究以及生化测定显示总蛋白和球蛋白增加,白蛋白水平降低。这些变化在第三周更为明显,随后进入下降阶段,到第六周几乎达到正常水平。电泳分析显示球蛋白水平升高也与免疫电泳分析中出现2条沉淀弧一致,表明抗体产生与高球蛋白血症之间存在相关性。

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