Elcock L H, Schoning P
Am J Vet Res. 1984 Nov;45(11):2380-4.
Forty-two pairs of testes and epididymides were obtained from clinically healthy cats and were examined histologically for age-related changes. All of the following testicular features increased with age: thickness of the testicular tunica adventitia, the amount of lipofuscin in the interstitial cell, hyperplasia of interstitial cells, vacuolation of Sertoli cell cytoplasm, degeneration of seminiferous tubules and thickness of the seminiferous tubular basement membrane. Two spermatoceles were found in the oldest cat. Age-related changes in the cat epididymis included increased thickness of the epididymal tunica adventitia, occasional intraepithelial cysts and hyperplasia of the epithelium, and one spermatocele in the head of the epididymal duct. Lymphocytic foci were common in testicular and epididymal connective tissue of cats of all ages and were reactive in the 2 oldest cats. Several changes were most frequent in 3- to 6.9-year-old cats: eosinophilic to amphophilic round cytoplasmic bodies in interstitial cells, proteinaceous tubular luminal debris, and spermatozoa in the epididymal duct. Cats less than 1 year old had significant (P less than 0.05) amounts of seminiferous tubular degeneration and a high percentage of epididymal intraepithelial cysts and hyperplasia.
从临床健康的猫身上获取了42对睾丸和附睾，并对其进行组织学检查以观察与年龄相关的变化。以下所有睾丸特征均随年龄增长而增加：睾丸外膜厚度、间质细胞中脂褐素的含量、间质细胞增生、支持细胞胞质空泡化、生精小管变性以及生精小管基底膜厚度。在最年长的猫身上发现了两个精液囊肿。猫附睾与年龄相关的变化包括附睾外膜厚度增加、偶尔出现的上皮内囊肿和上皮增生，以及附睾管头部的一个精液囊肿。淋巴细胞灶在所有年龄段猫的睾丸和附睾结缔组织中都很常见，在最年长的两只猫中呈反应性。3至6.9岁的猫出现几种变化最为频繁：间质细胞中嗜酸性至嗜两性的圆形胞质体、蛋白质性管腔碎片以及附睾管中的精子。小于1岁的猫有显著（P<0.05）数量的生精小管变性以及高比例的附睾上皮内囊肿和增生。
