Magnani M, Rossi L, Bechi G, De Rosa V
Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1659-61.
The hexokinase isozymic pattern of circulating reticulocytes fractionated by density gradient ultracentrifugation was studied. All the cellular fractions obtained show similar ratio of hexokinase Ia/hexokinase Ib while a four fold decay in specific activity was evidenced. Bone-marrow cells of anemic rabbits also contain low amounts of HK Ib while this isozymic form is not present in basophilic erythroblasts.
研究了通过密度梯度超速离心分离的循环网织红细胞的己糖激酶同工酶模式。获得的所有细胞组分显示己糖激酶Ia/己糖激酶Ib的比例相似,而比活性有四倍的下降。贫血兔的骨髓细胞也含有少量的HK Ib,而嗜碱性成红细胞中不存在这种同工酶形式。